This post is based on an analysis of a subset of the China Study II data, using HealthCorrelator for Excel (HCE), which is publicly available for download and use on a free trial basis. You can access the original data on the HCE web site, under “Sample datasets”.
HCE was designed to be used with small and individual personal datasets, but it can also be used with larger datasets for multiple individuals.
This analysis focuses on two main variables from the China Study II data: mortality in the 35-69 age range, and mortality in the 70-79 range. The table below shows the coefficients of association calculated by HCE for those two variables. The original variable labels are shown.
One advantage of looking at mortality in these ranges is that they are more likely to reflect the impact of degenerative diseases. Infectious diseases likely killed a lot of children in China at the time the data was being collected. Heart disease, on the other hand, is likely to have killed more people in the 35-69 and 70-79 ranges.
It is also good to have data for both ranges, because factors that likely increased longevity were those that were associated with decreased mortality in both ranges. For example, a factor that was strongly associated with mortality in the 35-69 range, but not the 70-79 range, might simply be very deadly in the former range.
The mortalities in both ranges are strongly correlated with each other, which is to be expected. Next, at the very top for both ranges, is sex. Being female is by far the variable with the strongest, and negative, association with mortality.
While I would expect females to live longer, the strengths of the associations make me think that there is something else going on here. Possibly different dietary or behavioral patterns displayed by females. Maybe smoking cigarettes or alcohol abuse was a lot less prevalent among them.
Markedly different lifestyle patterns between males and females may be a major confounding variable in the China Study sample.
Some of the variables are redundant; meaning that they are highly correlated and seem to measure the same thing. This is clear when one looks at the other coefficients of association generated by HCE.
For example, plant food consumption is strongly and negatively correlated with animal food consumption; so strongly that you could use either one of these two variables to measure the other, after inverting the scale. The same is true for consumption of rice and white flour.
Plant food consumption is not strongly correlated with plant protein consumption; many plant foods have little protein in them. The ones that have high protein content are typically industrialized and seed-based. The type of food most strongly associated with plant protein consumption is white flour, by far. The correlation is .645.
The figure below is based on the table above. I opened a separate instance of Excel, and copied the coefficients generated by HCE into it. Then I built two bar charts with them. The variable labels were replaced with more suggestive names, and some redundant variables were removed. Only the top 7 variables are shown, ordered from left to right on the bar charts in order of strength of association. The ones above the horizontal axis possibly increase mortality in each age range, whereas the ones at the bottom possibly decrease it.
When you look at these results as a whole, a few things come to mind.
White flour consumption doesn’t seem to be making people live longer; nor does plant food consumption in general. For white flour, it is quite the opposite. Plant food consumption reflects white flour consumption to a certain extent, especially in counties where rice consumption is low. These conclusions are consistent with previous analyses using more complex statistics.
Total food is positively associated with mortality in the 35-69 range, but not the 70-79 range. This may reflect the fact that folks who reach the age of 70 tend to naturally eat in moderation, so you don’t see wide variations in food consumption among those folks.
Eating in moderation does not mean practicing severe calorie restriction. This post suggests that calorie restriction doesn't seem to be associated with increased longevity in this sample. Eating well, but not too much, is.
The bar for rice (consumption) on the left chart is likely a mirror reflection of the white flour consumption, so it may appear to be good in the 35-69 range simply because it reflects reduced white flour consumption in that range.
Green vegetables seem to be good when you consider the 35-69 range, but not the 70-79 range.
Neither rice nor green vegetables seem to be bad either. For overall longevity they may well be neutral, with the benefits likely coming from their replacement of white flour in the diet.
Dietary fat seems protective overall, particularly together with animal foods in the 70-79 range. This may simply reflect a delayed protective effect of animal fat and protein consumption.
The protective effect of dietary fat becomes clear when we look at the relationship between carbohydrate calories and fat calories. Their correlation is -.957, which essentially means that carbohydrate intake seriously displaces fat intake.
Carbohydrates themselves may not be the problem, even if coming from high glycemic foods (except wheat flour, apparently). This post shows that they are relatively benign if coming from high glycemic rice, even at high intakes of 206 to 412 g/day. The problem seems to be caused by carbohydrates displacing nutrient-dense animal foods.
Interestingly, rice does not displace animal foods or fat in the diet. It is positively correlated with them. Wheat flour, on the other hand, displaces those foods. Wheat flour is negatively and somewhat strongly correlated with consumption of animal foods, as well as with animal fat and protein.
There are certainly several delayed effects here, which may be distorting the results somewhat. Degenerative diseases don’t develop fast and kill folks right away. They often require many years of eating and doing the wrong things to be fatal.
Sunday, January 30, 2011
Friday, January 28, 2011
Restaurant Style Meaty Marinara Sauce...
For a while now I have been wanting to try a new spaghetti recipe- one that is hardy, rich, and thick like ones they serve in an authentic Italian restaurants. I wanted something that you could use over spaghetti noodles, in a layered lasagna, or other pasta dishes and I think I have found and perfected the recipe I was dreaming of! I tried it out on my extended family this past week and got rave reviews... give it a whirl at your table, I am sure you will find the same great feedback! I have made it with both ground turkey and ground beef and I have served it over brown rice spaghetti and brown rice penne, either way it's delicious!
1 onion, chopped
3 cloves garlic, minced
2 TBSP grape seed oil
1 28 oz. can diced tomatoes
2 (6 oz) cans tomato paste
2 tsp. dried basil
2 tsp. dried oregano
2 bay leaves
1 tsp. sugar
1/2 cup red wine
2 lbs. ground meat (turkey or beef)
s & p
Directions:
In a large pot, add your grape seed oil and onion and saute for 2 minutes, then add your minced garlic and let that saute for another minute. Add your ground meat, turkey or beef, season it with salt and pepper and let it brown (I continually break up my meat because I like it really fine in this dish verses big chunks. If you are using beef, drain the fat once it's cooked before adding more ingredients.) Next, add everything else, stir well and let simmer for at least an hour- up to 3 if you have the time. You can also make this in the crock pot by following the same directions- still saute your onion and garlic and cook your meat on the stove- then add everything else to the crock pot to simmer all day long. Either way you choose to cook it, if it gets too thick, you may add up to a cup of water- but start at increments of 1/4 cup until you reach the consistency that you like. One last tip- I don't care for big chunks of tomatoes in this recipe, so I dump the can of diced tomatoes into my Vitamix for a few seconds to get them chopped even finer- and it's perfect!
***NOTE: This is a great recipe to freeze for later so keep that in mind when preparing it- do you want to set half of it aside or double it and keep it on hand for a night when you don't feel like cooking??? This is the perfect recipe for that!!!
Spicy Teff-Stuffed Mushrooms
Spicy Teff-stuffed Mushrooms |
These tasty mushroom are about as easy as an appetizer gets to prepare and to eat! Red pepper, ginger root, tamari and nutty teff add an interesting blend of flavors and a contrast of texture to entertain the mouth. Serve these delicious mushrooms with a plate of fresh basil leaves for wrapping and wedges of fresh lemon for spritzing, and you have the ultimate in finger food. Alternately, these make a great side dish to enhance the taste and variety of a Sunday brunch or light supper.
You'll need: 10 - 12 baby or button mushrooms, 1 tablespoon teff seed, 2 tablespoons olive oil, 1 garlic clove, 1 tablespoon tamari sauce, 1 tablespoon lemon juice, 1 teaspoon finely chopped ginger root, 1/2 teaspoon dried red chili pepper flakes, 1 teaspoon finely minced basil, 1/4 teaspoon each dried thyme, summer savory and oregano, whole fresh basil, lemon wedges
The Marinade: Whisk olive oil together with tamari and lemon juice. Mix in crushed and chopped garlic clove, chili pepper flakes, finely chopped ginger root and dried herbs.
The Mushrooms: Lightly rinse and wipe small mushrooms. Remove stems from caps.
White Button Mushrooms are ideal for miniature appetizers |
Place the stems and caps in marinade, coating them well. Allow to sit in marinade for at least 20 minutes (or overnight) in fridge.
Place mushrooms in Marinade and Coat well |
The Stuffing: Remove the mushrooms from the marinade, and set caps, cavity-side up, on a baking sheet. Chop stems in very small pieces, and set 1/4 of them aside, returning remainder of chopped stems to the marinade.
Lightly grind or crack teff seed |
Lightly grind the teff seed in a mortar and pestle or spice grinder, and put into the marinade. Add finely minced fresh basil leaves, and stir all ingredients together.
Using a spoon, fill each mushroom cap with a generous portion of teff-mushroom stem marinade, and top each cap with a sprinkling of reserved stems.
Baby Mushroom Caps are A Perfect Match for Tiny Teff |
To Cook:
Bake in a moderate oven, at 375 degrees, until mushroom
caps are juicy, and cooked to your preference.The teff will soften and swell, but will retain a delightful crunch, its nutty texture complementing the soft, chewy mushroom caps.
To Serve: Place mushroom caps on a small plate with fresh basil leaves and lemon wedges.
Crispy and Chewy, Spicy and Sweetly Savory |
To Serve: Place mushroom caps on a small plate with fresh basil leaves and lemon wedges.
With Zesty Lemon Wedge & Fresh Basil Leaves |
To Eat: Spritz a teff-stuffed mushroom cap with fresh lemon juice and wrap in a basil leaf. Pop into your mouth, and enjoy. Alternately, you could serve these spicy appetizers on pieces of brown bread, or simply eat with a knife and fork.
Wednesday, January 26, 2011
Healthy Spirits: New Stuff
Teff's Nutritional Profile
Nutrition Facts Serving Size | approx. 1/4 cup (45g) |
Amount Per Serving Calories 160 | Fat Cal. 10 |
% Daily Value* | |
Total Fat 1.0g | 2% |
Saturated Fat 0g | 0% |
Cholesterol 0mg | 0% |
Sodium 5mg | 0% |
Potassium 220mg | |
Total Carb. 32g | 11% |
Dietary Fiber 6g | 24% |
Sugars 0g |
Monday, January 24, 2011
HealthCorrelator for Excel (HCE) is now publicly available for free trial
HealthCorrelator for Excel (HCE) is now publicly available for download and use on a free trial basis. For those users who decide to buy it after trying, licenses are available for individuals and organizations. If you are a gym member, consider asking your gym to buy an organizational site license; this would allow the gym to distribute individual licenses at no cost to you and your colleagues.
HCE is a user-friendly Excel-based software that unveils important associations among health variables at the click of a button. Here are some of its main features:
- Easy to use yet powerful health management software.
- Estimates associations among any number of health variables.
- Automatically orders associations by decreasing absolute strength.
- Graphs relationships between pairs of health variables, for all possible combinations.
The beta testing was successfully completed, with fairly positive results. (Thank you beta testers!) Among beta testers were Mac users. The main request from beta testers was for more illustrative material on how to use HCE for specific purposes, such as losing body fat or managing blood glucose levels. This will be coming in the future in the form of posts and linked material.
To download a free trial version, good for 30 use sessions (which is quite a lot!), please visit the HealthCorrelator.com web site. There you will also find the software’s User Manual and various links to demo YouTube videos. You can also download sample datasets to try the software’s main features.
HCE is a user-friendly Excel-based software that unveils important associations among health variables at the click of a button. Here are some of its main features:
- Easy to use yet powerful health management software.
- Estimates associations among any number of health variables.
- Automatically orders associations by decreasing absolute strength.
- Graphs relationships between pairs of health variables, for all possible combinations.
The beta testing was successfully completed, with fairly positive results. (Thank you beta testers!) Among beta testers were Mac users. The main request from beta testers was for more illustrative material on how to use HCE for specific purposes, such as losing body fat or managing blood glucose levels. This will be coming in the future in the form of posts and linked material.
To download a free trial version, good for 30 use sessions (which is quite a lot!), please visit the HealthCorrelator.com web site. There you will also find the software’s User Manual and various links to demo YouTube videos. You can also download sample datasets to try the software’s main features.
Friday, January 21, 2011
Teff: An Ancient Grain for Contemporary Cuisine
Teff is one of my favorite grains to cook, and to eat. It is a tiny, tiny grain about the size of a poppy seed and has a mild, nutty flavor with a slightly sweet taste. An well-known organic chef describes it as "reminiscent of chocolate, hazelnuts, and molasses" (Leslie Cerier. Gluten-free Recipes for the Conscious Cook, p. 21) The grain comes in a variety of colors, from white and red to dark brown, and the lighter the seed, the milder the flavor.
Described as eco-friendly, Teff grows well in a wide variety of farming conditions from arid to very wet or marginal land. This ancient grain clearly is a better choice for the environment than many chemical-dependent modern hybrid grains. Indigenous to the hills of Ethiopia and Eritrea, teff can withstand high heat, and bright sunlight, thriving in unpredictable and difficult climates. The heritage grain traces its history back thousands of years to the ancient civilizations of Abyssinia. I’ve been told that the word ‘teff’ means ‘lost’ , the grain being so small that if it is ever dropped, it is lost and gone.
The semi-nomadic peoples of the regions were able to easily carry enough seed in their peregrinations to sow adequate crops to feed their community. Today teff still comprises the staple grain of the cuisine of modern Ethiopian and Eritrean, and ex-patriot communities world-wide. For most people, a taste of teff is truly 'love at first bite'. Like all other grains, teff's nutrients concentrate in the germ and the bran. Because of its tiny size, the germ and the bran make up almost the whole grain. Since teff is too small to hull or refine, it maintains its nutritional integrity as a whole grain in whatever form it is found.
Field of Teff |
Described as eco-friendly, Teff grows well in a wide variety of farming conditions from arid to very wet or marginal land. This ancient grain clearly is a better choice for the environment than many chemical-dependent modern hybrid grains. Indigenous to the hills of Ethiopia and Eritrea, teff can withstand high heat, and bright sunlight, thriving in unpredictable and difficult climates. The heritage grain traces its history back thousands of years to the ancient civilizations of Abyssinia. I’ve been told that the word ‘teff’ means ‘lost’ , the grain being so small that if it is ever dropped, it is lost and gone.
|
The semi-nomadic peoples of the regions were able to easily carry enough seed in their peregrinations to sow adequate crops to feed their community. Today teff still comprises the staple grain of the cuisine of modern Ethiopian and Eritrean, and ex-patriot communities world-wide. For most people, a taste of teff is truly 'love at first bite'. Like all other grains, teff's nutrients concentrate in the germ and the bran. Because of its tiny size, the germ and the bran make up almost the whole grain. Since teff is too small to hull or refine, it maintains its nutritional integrity as a whole grain in whatever form it is found.
Tiny grains of Teff |
Since it is a nutritional powerhouse, people with special dietary considerations and many professional athletes enjoy including Teff in their diets. Not only does this ancient grain have a delicious flavor, but also it is gluten-free, and provides the body with readily available, easily-digested protein and high quality complex carbohydrates, proteins, minerals and fiber.
An eight-ounce serving of teff provides 32% of the RDA for calcium, 80% RDA for iron, and contains 28 grams of protein. Teff is low in fat (4 grams per 8-ounce serving), high in fiber (36 grams per 8-ounce serving), and is a good source of niacin, thiamine, riboflavin, zinc, magnesium, copper, manganese, boron, phosphorous and potassium.
An 8-ounce serving of teff seed |
An eight-ounce serving of teff provides 32% of the RDA for calcium, 80% RDA for iron, and contains 28 grams of protein. Teff is low in fat (4 grams per 8-ounce serving), high in fiber (36 grams per 8-ounce serving), and is a good source of niacin, thiamine, riboflavin, zinc, magnesium, copper, manganese, boron, phosphorous and potassium.
Grinding Teff into Whole Grain Flour |
Ground into flour, teff is extraordinarily versatile. In Ethiopian and Eritrean cuisines, it is used to make traditional large flat sour dough called injera.This bread is cooked on one side, and full of air-bubble holes on the other, much like an English crumpet. Injera has a nutty, tangy taste that complements most flavors, particularly the exotic spices of this African cuisine. A variety of spicy entrées, and a wat or thick vegetable stew are served on top of the bread.
Injera, a teff flour sour dough bread |
Instead of cutlery, pieces of injera are used to scoop up the various dishes, often from a central platter.
Coming soon: An Excellent Appetizer
"Teff-stuffed Mushrooms"
Healthy Spirits: The New Stuff: Midnight Sun and More!
Thursday, January 20, 2011
Healthy Spirits: Sink the Bismarck and Tactical Nuclear Penguin!!!
Very limited quantities. Only Beer of the Month Club members may reserve bottles. To reserve, call us at 415-255-0610. Please do not reserve by e-mail, as we may not be able to respond in time to guarantee you a bottle. These are expected to go fast.
1. Tactical Nuclear Penguin
-32%ABV Imperial Stout
2.Sink The Bismarck!
-41% ABV Imperial IPA
cheers,
dave hauslein
beer manager
415-255-0610
1. Tactical Nuclear Penguin
-32%ABV Imperial Stout
2.Sink The Bismarck!
-41% ABV Imperial IPA
cheers,
dave hauslein
beer manager
415-255-0610
Wednesday, January 19, 2011
Healthy Spirits: Crispin Cider and more!
Tuesday, January 18, 2011
Healthy Spirits: New Arrivals
1. Upright Brewing "Four" Saison
2. Upright Brewing "Five" Saison
3. Upright Brewing "Six" Saison
4. Upright Brewing "Seven" Saison
5. Prof. Fritz Briem 1809 Berliner Weisse
6. Prof. Fritz Briem 13th Century Grut Bier
COMING TOMORROW:
Dogfish Head Burton Baton!!!
cheers,
dave hauslein
beer manager
415-255-0610
2. Upright Brewing "Five" Saison
3. Upright Brewing "Six" Saison
4. Upright Brewing "Seven" Saison
5. Prof. Fritz Briem 1809 Berliner Weisse
6. Prof. Fritz Briem 13th Century Grut Bier
COMING TOMORROW:
Dogfish Head Burton Baton!!!
cheers,
dave hauslein
beer manager
415-255-0610
Lentil Soup...
It's a cold and gloomy day here, so I thought a crock pot recipe for a warm soup might come in handy. This one is simple, low in fat, high in fiber.
Ingredients:
1 cup carrots, chopped
1 cup onion, chopped
1 cup celery, chopped
1 cup lentils
2 cloves garlic, minced
1 bay leaf
5 cups chicken broth, regular or low sodium
8 oz. tomato sauce
1/3 lb. ground turkey, browned
1/2 tsp oregano
1/4 tsp thyme
1/4 tsp basil
1/4 tsp pepper
Directions:
Brown your turkey meat on your stove, I season mine with s & p & garlic powder while it's cooking. Then dump everything in your crock pot and cook on low for 8 hours. Stir occasionally of you are home. Remove the bay leaf before serving. That's it!
Variations: I have made this with 1/3 pound, 1/2 pound and 1 pound of turkey before and it turns out great either way you choose... just depends what you are in the mood for. You could also omit the turkey and add some beans if you want to go the vegan route! Get creative!
Saturday, January 15, 2011
Do you lose muscle if you lift weights after a 24-hour fast? Probably not if you do that regularly
Compensatory adaptation (CA) is an idea that is useful in the understanding of how the body reacts to inputs like dietary intake of macronutrients and exercise. CA is a complex process, because it involves feedback loops, but it leads to adaptations that are fairly general, applying to a large cross-section of the population.
A joke among software developers is that the computer does exactly what you tell it to do, but not necessarily what you want it to do. Similarly, through CA your body responds exactly to the inputs you give it, but not necessarily in the way you would like it to respond. For example, a moderate caloric deficit may lead to slow body fat loss, while a very high caloric deficit may bring body fat loss to a halt.
Strength training seems to lead to various adaptations, which can be understood through the lens provided by CA. One of them is a dramatic increase in the ability of the body to store glycogen, in both liver and muscle. Glycogen is the main fuel used by muscle during anaerobic exercise. Regular strength training causes, over time, glycogen stores to more than double. And about 2.6 the amount of glycogen is also stored as water.
When one looks bigger and becomes stronger as a result of strength training, that is in no small part due to increases in glycogen and water stored. More glycogen stored in muscle leads to more strength, which is essentially a measure of one’s ability to move a certain amount of weight around. More muscle protein is also associated with more strength.
Thinking in terms of CA, the increase in the body’s ability to store glycogen is to be expected, as long as glycogen stores are depleted and replenished on a regular basis. By doing strength training regularly, you are telling your body that you need a lot of glycogen on a regular basis, and the body responds. But if you do not replenish your glycogen stores on a regular basis, you are also sending your body a conflicting message, which is that dietary sources of the substances used to make glycogen are not readily available. Among the substances that are used to make glycogen, the best seems to be the combination of fructose and glucose that one finds in fruits.
Let us assume a 160-lbs untrained person, John, who stored about 100 g of glycogen in his liver, and about 500 g in his muscle cells, before starting a strength training program. Let us assume, conservatively, that after 6 months of training he increased the size of his liver glycogen tank to 150 g. Muscle glycogen storage was also increased, but that is less relevant for the discussion in this post.
Then John fasted for 24 hours before a strength training session, just to see what would happen. While fasting he went about his business, doing light activities, which led to a caloric expenditure of about 100 calories per hour (equivalent to 2400 per day). About 20 percent of that, or 20 calories per hour, came from a combination of blood glucose and ketones. Contrary to popular belief, ketones can always be found in circulation. If only glucose were used, 5 g of glucose per hour would be needed to supply those 20 calories.
During the fast, John’s glucose needs, driven primarily by his brain’s needs, were met by conversion of liver glycogen to blood glucose. His muscle glycogen was pretty much “locked” during the fast; because he was doing only light activities, which rely primarily on fat as fuel. Muscle glycogen is “unlocked” through anaerobic exercise, of which strength training is an instance.
One of the roles of ketones is to spare liver glycogen, delaying the use of muscle protein to make glucose down the road, so the percentage of ketones in circulation in John’s body increased in a way that was inversely proportional to stored liver glycogen. According to this study, after 72 hours fasting about 25 percent of the body’s glucose needs are met by ketones. (This may be an underestimation.)
If we assume a linear increase in ketone concentration, this leads to a 0.69 percent increase in circulating ketones for every 2-hour period. (This is a simplification, as the increase is very likely nonlinear.) So, when we look at John’s liver glycogen tank, it probably went down in a way similar to that depicted on the figure below. The blue bars show liver glycogen at the end of each 2-hour period. The red bars show the approximate amount of glucose consumed during each 2-hour period. Glucose consumed goes down as liver glycogen decreases, because of the increase in blood ketones.
As you can see, after a 24-hour fast, John had about 35 g of glycogen left, which is enough for a few extra hours of fasting. At the 24-hour mark the body had no need to be using muscle protein to generate glucose. Maybe some of that happened, but probably not much if John was relaxed during the fast. (If he was stressed out, stress hormones would have increased blood glucose release significantly.) From the body’s perspective, muscle is “expensive”, whereas body fat is “cheap”. And body fat, converted to free fatty acids, is what is used to produce ketones during a fast.
Blood ketone concentration does not go up dramatically during a 24-hour fast, but it does after a 48-hour fast, when it becomes about 10 times higher. This major increase occurs primarily to spare muscle, including heart muscle. If the increase is much smaller during a 24-hour fast, one can reasonably assume that the body is not going to be using muscle during the fast. It can still rely on liver glycogen, together with a relatively small amount of ketones.
Then John did his strength training, after the 24-hour fast. When he did that, the muscles he used in the exercise session converted locally stored glycogen into lactate. A flood of lactate was secreted into the bloodstream, which was used by his liver to produce glucose and also to replenish liver glycogen a bit. Again, at this stage there was no need for John’s body to use muscle protein to generate glucose.
Counterintuitive as this may sound, the more different muscles John used, the more lactate was made available. If John did 20 sets of isolated bicep curls, for example, his body would not have released enough lactate to meet its glucose needs or replenish liver glycogen. As a result, stress hormones would go up a lot, and his body would send him some alarm signals. One of those signals is a feeling of “pins and needles”, which is sometimes confused with the symptoms of a heart attack.
John worked out various muscle groups for 30 minutes or so, and he did not even feel fatigued. He felt energetic, in part because his blood glucose went up a lot, peaking at 150 mg/dl, to meet muscle needs. This elevated blood glucose was caused by his liver producing blood glucose based on lactate and releasing it into his blood. Muscle glycogen was depleted as a result of that.
Do you lose any muscle if you lift weights after a 24-hour fast?
I don’t think so, if you deplete your glycogen stores by doing strength training on a regular basis, and also replenish them on a regular basis. In fact, your liver glycogen tank will increase in size, and you may find yourself being able to fast for many hours without feeling hungry.
You will feel hungry after the strength training session following the fast though; probably ravenous.
References
Brooks, G.A., Fahey, T.D., & Baldwin, K.M. (2005). Exercise physiology: Human bioenergetics and its applications. Boston, MA: McGraw-Hill.
Wilmore, J.H., Costill, D.L., & Kenney, W.L. (2007). Physiology of sport and exercise. Champaign, IL: Human Kinetics.
A joke among software developers is that the computer does exactly what you tell it to do, but not necessarily what you want it to do. Similarly, through CA your body responds exactly to the inputs you give it, but not necessarily in the way you would like it to respond. For example, a moderate caloric deficit may lead to slow body fat loss, while a very high caloric deficit may bring body fat loss to a halt.
Strength training seems to lead to various adaptations, which can be understood through the lens provided by CA. One of them is a dramatic increase in the ability of the body to store glycogen, in both liver and muscle. Glycogen is the main fuel used by muscle during anaerobic exercise. Regular strength training causes, over time, glycogen stores to more than double. And about 2.6 the amount of glycogen is also stored as water.
When one looks bigger and becomes stronger as a result of strength training, that is in no small part due to increases in glycogen and water stored. More glycogen stored in muscle leads to more strength, which is essentially a measure of one’s ability to move a certain amount of weight around. More muscle protein is also associated with more strength.
Thinking in terms of CA, the increase in the body’s ability to store glycogen is to be expected, as long as glycogen stores are depleted and replenished on a regular basis. By doing strength training regularly, you are telling your body that you need a lot of glycogen on a regular basis, and the body responds. But if you do not replenish your glycogen stores on a regular basis, you are also sending your body a conflicting message, which is that dietary sources of the substances used to make glycogen are not readily available. Among the substances that are used to make glycogen, the best seems to be the combination of fructose and glucose that one finds in fruits.
Let us assume a 160-lbs untrained person, John, who stored about 100 g of glycogen in his liver, and about 500 g in his muscle cells, before starting a strength training program. Let us assume, conservatively, that after 6 months of training he increased the size of his liver glycogen tank to 150 g. Muscle glycogen storage was also increased, but that is less relevant for the discussion in this post.
Then John fasted for 24 hours before a strength training session, just to see what would happen. While fasting he went about his business, doing light activities, which led to a caloric expenditure of about 100 calories per hour (equivalent to 2400 per day). About 20 percent of that, or 20 calories per hour, came from a combination of blood glucose and ketones. Contrary to popular belief, ketones can always be found in circulation. If only glucose were used, 5 g of glucose per hour would be needed to supply those 20 calories.
During the fast, John’s glucose needs, driven primarily by his brain’s needs, were met by conversion of liver glycogen to blood glucose. His muscle glycogen was pretty much “locked” during the fast; because he was doing only light activities, which rely primarily on fat as fuel. Muscle glycogen is “unlocked” through anaerobic exercise, of which strength training is an instance.
One of the roles of ketones is to spare liver glycogen, delaying the use of muscle protein to make glucose down the road, so the percentage of ketones in circulation in John’s body increased in a way that was inversely proportional to stored liver glycogen. According to this study, after 72 hours fasting about 25 percent of the body’s glucose needs are met by ketones. (This may be an underestimation.)
If we assume a linear increase in ketone concentration, this leads to a 0.69 percent increase in circulating ketones for every 2-hour period. (This is a simplification, as the increase is very likely nonlinear.) So, when we look at John’s liver glycogen tank, it probably went down in a way similar to that depicted on the figure below. The blue bars show liver glycogen at the end of each 2-hour period. The red bars show the approximate amount of glucose consumed during each 2-hour period. Glucose consumed goes down as liver glycogen decreases, because of the increase in blood ketones.
As you can see, after a 24-hour fast, John had about 35 g of glycogen left, which is enough for a few extra hours of fasting. At the 24-hour mark the body had no need to be using muscle protein to generate glucose. Maybe some of that happened, but probably not much if John was relaxed during the fast. (If he was stressed out, stress hormones would have increased blood glucose release significantly.) From the body’s perspective, muscle is “expensive”, whereas body fat is “cheap”. And body fat, converted to free fatty acids, is what is used to produce ketones during a fast.
Blood ketone concentration does not go up dramatically during a 24-hour fast, but it does after a 48-hour fast, when it becomes about 10 times higher. This major increase occurs primarily to spare muscle, including heart muscle. If the increase is much smaller during a 24-hour fast, one can reasonably assume that the body is not going to be using muscle during the fast. It can still rely on liver glycogen, together with a relatively small amount of ketones.
Then John did his strength training, after the 24-hour fast. When he did that, the muscles he used in the exercise session converted locally stored glycogen into lactate. A flood of lactate was secreted into the bloodstream, which was used by his liver to produce glucose and also to replenish liver glycogen a bit. Again, at this stage there was no need for John’s body to use muscle protein to generate glucose.
Counterintuitive as this may sound, the more different muscles John used, the more lactate was made available. If John did 20 sets of isolated bicep curls, for example, his body would not have released enough lactate to meet its glucose needs or replenish liver glycogen. As a result, stress hormones would go up a lot, and his body would send him some alarm signals. One of those signals is a feeling of “pins and needles”, which is sometimes confused with the symptoms of a heart attack.
John worked out various muscle groups for 30 minutes or so, and he did not even feel fatigued. He felt energetic, in part because his blood glucose went up a lot, peaking at 150 mg/dl, to meet muscle needs. This elevated blood glucose was caused by his liver producing blood glucose based on lactate and releasing it into his blood. Muscle glycogen was depleted as a result of that.
Do you lose any muscle if you lift weights after a 24-hour fast?
I don’t think so, if you deplete your glycogen stores by doing strength training on a regular basis, and also replenish them on a regular basis. In fact, your liver glycogen tank will increase in size, and you may find yourself being able to fast for many hours without feeling hungry.
You will feel hungry after the strength training session following the fast though; probably ravenous.
References
Brooks, G.A., Fahey, T.D., & Baldwin, K.M. (2005). Exercise physiology: Human bioenergetics and its applications. Boston, MA: McGraw-Hill.
Wilmore, J.H., Costill, D.L., & Kenney, W.L. (2007). Physiology of sport and exercise. Champaign, IL: Human Kinetics.
Friday, January 14, 2011
New Arrivals: Victory Twelve, Grande Dame Oud Bruin and more
Thursday, January 13, 2011
A Cabbage Casserole with Grilled Vegetables and Deep Fried Tofu
Piping hot from the oven and ready to serve |
A delightful one-dish meal, this cabbage casserole is chock-full of tasty deep fried tofu, grilled mushrooms and marinaded vegetables. Easy to make, this recipe is a perfect choice for a chilly winter's day, keeping the cold at bay with its nutrient-rich ingredients and spicy flavor.
Local organic ingredients |
You'll need: 1 1/2 cups thinly sliced cabbage, 1/2 cup coarsely grated carrots, 1/2 cup sliced mushrooms, 1/4 cup chopped cherry tomatoes, 1/2 cup cubed zucchini, 1 tablespoon lightly chopped garlic pearls or 1 garlic clove, 1/2 cup cubed deep fried tofu, 1 tablespoon lemon juice, 2 tablespoons olive oil, 1 tablespoon finely chopped ginger root, 1 tablespoon apple cider vinegar, 1 tablespoon agave syrup, 1/4 cup water, 1 teaspoon dried red chili flakes, 1 teaspoon dried oregano and thyme, 1/8 teaspoon Himalayan salt.
cabbage noodles |
The Noodles:
Slice cabbage into long thin strips to resemble noodles. Coarsely grate the carrots. Crush and lightly chop garlic pearls, or garlic clove. Stir together apple cider vinegar, agave syrup, and water. Place vegetables in an oven-proof dish and pour over cabbage-carrot mixture. Sprinkle with salt, dried oregano and thyme.
Cabbage and carrots ready for the oven |
Marinaded vegetables ready for Grilling |
The Vegetables:
While cabbage is cooking, whisk lemon juice and olive oil together. Add chopped ginger root and dried red chili pepper flakes. Add thinly sliced mushrooms, quartered cherry tomatoes, and cubed zucchini to the dressing. Let vegetables marinade until cabbage is ready to remove from oven. Transfer vegetables to broiling pan, and grill until tomatoes are bubbling, and mushrooms are juicy.
Deep Fried Tofu |
The Tofu:
Cut deep fried tofu into small cubes.
Adding Tofu and Vegetables |
When grilled vegetables are ready, add them and the tofu to cabbage and carrot mix. Carefully stir ingredients together, cover and return to oven (350) for 5 minutes to blend flavors and heat through.
A warming meal for a chilly winter's day |
Enjoy this filling casserole on its own for a light lunch, or serve with a garden salad and brown bread for a more substantial supper.
Wednesday, January 12, 2011
Roasted Butternut Squash
This was a really fun use of my Butternut Squash that I got this week at Abundant Harvest Organics, our local CSA. It made a great side dish and my daughter loved them- if you like Sweet Potato Fries, you will probably like these too! Sorry about the bad picture... don't let it stop you!
Ingredients:
1-2 butternut squash
grape seed oil
sea salt
pepper
Alternative Spices:
cinnamon, ground ginger, and nutmeg
Directions:
Preheat your oven to 425. Cut your squash in half (vertically & then horizontally) then peel the outside "skin" off with a paring knife and deseed the inside cavity. Then slice your squash in thin slices, put it in a bowl and drizzle grapeseed oil on top. Sprinkle with seasoning- either sea salt and pepper OR cinnamon, ginger, and nutmeg. Then spread them out on a roasting pan so that none of them are touching and bake for 35-45 minutes or until they begin to brown and edges are crisp. Let cool for a minute or two then begin snacking- YUM!
Tuesday, January 11, 2011
Why Grape Seed Oil???
I received a comment the other day asking about the difference between Grape Seed Oil and Olive Oil and when I use which and why... so here's a brief breakdown of MY understanding...
I switched over to Grape Seed Oil with my cooking when I first heard about the high Smoke Point it has (421 degrees F) which means that you can use it to cook food up to that temperature without the oil breaking down or deteriorating or really changing flavor. Olive Oil on the other hand has a lower Smoke Point (350 degrees F) which means that when you cook with it, be it sauteing, frying, or baking it will begin to break down, change flavors, and possibly even let off a toxicity which you can often smell when cooking with it at high temperatures. So almost always, I use Grape Seed Oil when cooking with heat- with the exception of Coconut Oil (I use that when cooking eggs and when making baked goods, it's Smoke Point is 360 for reference) and I leave my Olive Oil for "cold cooking" such as salad dressings and the like.
All 3 oils that I mentioned above have great health benefits as well. For instance, Grape Seed Oil contains antioxidants as well as Vitamin E & C and beta-carotene. It has also been shown to lower LDL cholesterol ("bad cholesterol") and increase HDL ("good cholesterol"). Similar findings have been shown with Olive Oil, as well as it's benefits for the heart and preventions of cancer.
Monday, January 10, 2011
How come evolution hasn’t made us immortal? Death, like sex, helps animal populations avoid extinction
Genes do not evolve, nor do traits that are coded for our genes. We say that they evolve to facilitate discourse, which is alright. Populations evolve. A new genotype appears in a population and then either spreads or disappears. If it spreads, then the population is said to be evolving with respect to that genotype. A genotype may spread to an entire population; in population genetics, this is called “fixation”.
Asexual reproduction is very uncommon among animals. The most accepted theory to explain this is that animal populations live in environments that change very quickly, and thus need a great deal of genetic diversity within them to cope with the change. Otherwise they disappear, and so do their genes. Asexual reproduction leads to dramatically less genetic diversity in populations than sexual reproduction.
Asexual reproduction is similar to cloning. Each new individual looks a lot like its single parent. This does not work well in populations where individuals live relatively long lives. And even 1 year may be too long in this respect. It is just too much time to wait for a possible new mutation that will bring in some genetic diversity. To complicate matters, genetic mutation does not occur very often, and most genetic mutations are neutral with respect to the phenotype (i.e., they don’t code for any trait).
This is not so much of a problem for species whose members reproduce extremely fast; e.g., produce a new generation in less than 1 hour. A fast-reproducing species usually has a short lifespan as well. Accordingly, asexual reproduction is common among short-lived and fast-reproducing unicellular organisms and pathogens that have no cell structure like viruses.
Bacteria and viruses, in particular, form a part of the environment in which animals live that require animal populations to have a large amount of genetic diversity. Animal populations with low genetic diversity are unlikely to be able to cope with the barrage of diseases caused by these fast-mutating parasites.
We make sex chiefly because of the parasites.
And what about death? What does it bring to the table for a population?
Let us look at the other extreme – immortality. Immortality is very problematic in evolutionary terms because a population of immortal individuals would quickly outgrow its resources. That would happen too fast for the population to evolve enough intelligence to be able to use resources beyond those that were locally available.
In this post I assume that immortality is not the same as indestructibility. Here immortality is equated to the absence of aging as we know it. In this sense, immortals can still die by accident or due to disease. They simply do not age. For immortals, susceptibility to disease does not go up with age.
One could argue that a population of immortal individuals who did not reproduce would have done just fine. But that is not correct, because in this case immortality would be akin to cloning, but worse. Genetic diversity would not grow, as no mutations would occur. The fixed population of immortals would be unable to cope with fast-mutating parasites.
There is so much selection pressure against immortality in nature that it is no surprise that animals of very few species live more than 60 years on average. Humans are at the high end of the longevity scale. They are there for a few reasons. One is that our ancestors had offspring that required extra care, which led to an increase in the parents’ longevity. The offspring required extra care chiefly because of their large brains.
That increase in longevity was likely due to genetic mutations that helped our ancestors extend a lifespan that was programmed to be relatively short. Immortality is not a sound strategy for population survival, and thus there are probably many mechanisms through which it is prevented.
Death is evolution’s main ally. Sex is a very good helper. Both increase genetic diversity in populations.
We can use our knowledge of evolution to live better today. The aging clock can be slowed significantly via evolutionarily sound diet and lifestyle changes, essentially because some of our modern diet and lifestyle choices accelerate aging a lot. But diet and lifestyle changes probably will not make people live to 150.
If we want to become immortal, as we understand it in our current human form, ultimately we may want to beat evolution. In this sense, only very intelligent beings can become immortal.
Maybe we can achieve that by changing our genes, or by learning how to transfer our consciousness “software” into robots. In doing so, however, we may become something different; something that is not human and thus doesn’t see things in the same way as a human does. A conscious robot, without the hormones that so heavily influence human behavior, may find that being alive is pointless.
There is another problem. What if the only natural way to achieve some form of immortality is through organic death, but in a way that we don’t understand? This is not a matter of faith or religion. There are many things that we don’t know for sure. This is probably the biggest mystery of all; one that we cannot unravel in our current human state.
(Human chromosomes capped by telomeres, the white areas at the ends. Telomere shortening is caused by oxidative stress, and seems to be associated with death of cells and organisms. Source: Wikipedia.)
Asexual reproduction is very uncommon among animals. The most accepted theory to explain this is that animal populations live in environments that change very quickly, and thus need a great deal of genetic diversity within them to cope with the change. Otherwise they disappear, and so do their genes. Asexual reproduction leads to dramatically less genetic diversity in populations than sexual reproduction.
Asexual reproduction is similar to cloning. Each new individual looks a lot like its single parent. This does not work well in populations where individuals live relatively long lives. And even 1 year may be too long in this respect. It is just too much time to wait for a possible new mutation that will bring in some genetic diversity. To complicate matters, genetic mutation does not occur very often, and most genetic mutations are neutral with respect to the phenotype (i.e., they don’t code for any trait).
This is not so much of a problem for species whose members reproduce extremely fast; e.g., produce a new generation in less than 1 hour. A fast-reproducing species usually has a short lifespan as well. Accordingly, asexual reproduction is common among short-lived and fast-reproducing unicellular organisms and pathogens that have no cell structure like viruses.
Bacteria and viruses, in particular, form a part of the environment in which animals live that require animal populations to have a large amount of genetic diversity. Animal populations with low genetic diversity are unlikely to be able to cope with the barrage of diseases caused by these fast-mutating parasites.
We make sex chiefly because of the parasites.
And what about death? What does it bring to the table for a population?
Let us look at the other extreme – immortality. Immortality is very problematic in evolutionary terms because a population of immortal individuals would quickly outgrow its resources. That would happen too fast for the population to evolve enough intelligence to be able to use resources beyond those that were locally available.
In this post I assume that immortality is not the same as indestructibility. Here immortality is equated to the absence of aging as we know it. In this sense, immortals can still die by accident or due to disease. They simply do not age. For immortals, susceptibility to disease does not go up with age.
One could argue that a population of immortal individuals who did not reproduce would have done just fine. But that is not correct, because in this case immortality would be akin to cloning, but worse. Genetic diversity would not grow, as no mutations would occur. The fixed population of immortals would be unable to cope with fast-mutating parasites.
There is so much selection pressure against immortality in nature that it is no surprise that animals of very few species live more than 60 years on average. Humans are at the high end of the longevity scale. They are there for a few reasons. One is that our ancestors had offspring that required extra care, which led to an increase in the parents’ longevity. The offspring required extra care chiefly because of their large brains.
That increase in longevity was likely due to genetic mutations that helped our ancestors extend a lifespan that was programmed to be relatively short. Immortality is not a sound strategy for population survival, and thus there are probably many mechanisms through which it is prevented.
Death is evolution’s main ally. Sex is a very good helper. Both increase genetic diversity in populations.
We can use our knowledge of evolution to live better today. The aging clock can be slowed significantly via evolutionarily sound diet and lifestyle changes, essentially because some of our modern diet and lifestyle choices accelerate aging a lot. But diet and lifestyle changes probably will not make people live to 150.
If we want to become immortal, as we understand it in our current human form, ultimately we may want to beat evolution. In this sense, only very intelligent beings can become immortal.
Maybe we can achieve that by changing our genes, or by learning how to transfer our consciousness “software” into robots. In doing so, however, we may become something different; something that is not human and thus doesn’t see things in the same way as a human does. A conscious robot, without the hormones that so heavily influence human behavior, may find that being alive is pointless.
There is another problem. What if the only natural way to achieve some form of immortality is through organic death, but in a way that we don’t understand? This is not a matter of faith or religion. There are many things that we don’t know for sure. This is probably the biggest mystery of all; one that we cannot unravel in our current human state.
Sunday, January 9, 2011
Chicken Fried Rice
This is a great "all-in-one" meal that has a healthy grain (brown rice), some protein (eggs & chicken) and TONS of Veggies!! My favorite recipe I've tried so far for Fried Rice... I think you'll like it too!
Ingredients:2 cups brown rice
4 cups water
2 TBSP Grape Seed oil
3 eggs, beaten
2 cloves garlic, minced
1/4 tsp ginger
1 cup carrots, shredded
1 red bell pepper, diced
4 scallions, thinly sliced
1/2 cup frozen peas
1/3 cup tamari soy sauce
1 TBSP sesame seeds
1-2 chicken breasts, diced
s & p
Directions:
There are s few different steps going on in this dish- Step 1: you need to cook your rice, so get your 4 cups water boiling and then add your brown rice letting it cook per directions on package. Step 2: While that's going, wash and dice your chicken breasts and throw them in a skillet with a drizzle of Grape Seed Oil and give them a sprinkle of salt and pepper. Let them cook up until they are nice and browned. Step 3: in a large skillet or a wok, add your 2 TBSP Grape Seed Oil and your scrambled eggs. Cook them like you would scrambled eggs, then push them to the outside edges of your pan and add your chopped bell pepper, carrots, garlic, and ginger to the middle of the pan and let them cook that for 3-4 minutes, stirring occasionally. Last step it so put it all together. So, when your rice is done, add your rice, frozen peas, cooked chicken from your other skillet, your soy sauce, and sesame seeds and keep turning it over until all the ingredients are well mixed. I serve this for dinner. It makes a ton- enough for 4 people to eat as a meal with some left overs! It's a perfect combination or a healthy grain, veggies, and some chicken for protein! Enjoy!!!
Gluten Free: This meal can easily be made Gluten Free by using Tamari Sauce and Brown rice.
Vegan: This is also an easy Vegan Recipe by omitting the chicken and eggs.
Friday, January 7, 2011
The Abyss back on the shelves
Ding ding,
And in this corner, wearing brown and black trunks and weighing in at 22 OZ, with the delicious flavors of licorice, molasses and oak, none other than Deschutes "The Abyss" A.K.A the Northern Dandy. Ordering the Abyss this year has been kind of like going a couple rounds in a heavy weight championship fight. Fortunately we channeled our inner Rocky Balboa and scored a few more precious cases for our beloved following. Next year I hear we have to fight Hulk Hogan or Mr. T or something like that.....
Drink up
Nate
Thursday, January 6, 2011
New Year New Arrivals: Victory At Sea, Dogfish Pangaea, Mikkeller Chipotle Porter and more!
Come drink in the the new year proper with Healthy Spirits! Big big big order today. Limited quantities on most of the stuff, so get it while you can.
-Ballast Point Victory At Sea
-Ballast Point Sculpin (Fresh Batch)
-Dogfish Head Pangaea
-Mikkeller Chipotle Porter
-Mikkeller/Brew Dog I Hardcore You
-Drie Fonteinen Oude Geuze
-HaandBryggeriet Royk Uten Ild- "smoke without fire" (Norwegian smoked ale)
-Nogne O Dugges Sahti
-Amager Bryghus Rye Porter
-Saint Somewhere Pays du Soleil
-Fantome Saison
-21st Amendment Back in Black
-Cucapa Barley Wine
-Dupont Biere de Miel
-Flying Dog Double Dog
-Flying Dog Gonzo Porter
-Shipyard Imperial Porter
-Hitachino Japanese Classic
Damn, that was a lot. Well I guess it's a good day to be a beer enthusiast!
Nate
Does strength exercise increase nitrogen balance?
This previous post looks at the amounts of protein needed to maintain a nitrogen balance of zero. It builds on data about individuals doing endurance exercise, which increases the estimates a bit. The post also examines the issue of what happens when more protein than is needed in consumed; including by people doing strength exercise.
What that post does not look into is whether strength exercise, performed at the anaerobic range, increases nitrogen balance. If it did, it may lead to a counterintuitive effect: strength exercise, when practiced at a certain level of intensity, might enable individuals in calorie deficit to retain their muscle, and lose primarily body fat. That is, strength exercise might push the body into burning more body fat and less muscle than it would normally do under calorie deficit conditions.
Under calorie deficit people normally lose both body fat and muscle to meet caloric needs. About 25 percent of lean body mass is lost in sedentary individuals, and 33 percent or more in individuals performing endurance exercise. I suspect that strength exercise has the potential to either bring this percentage down to zero, or to even lead to muscle gain if the calorie deficit is very small. One of the reasons is the data summarized on this post.
Two other reasons are related to what happens with children, and the variation in spontaneous hunger up-regulation in response to various types of exercise. The first reason can be summarized as this: it is very rare for children to be in negative nitrogen balance (Brooks et al., 2005); even when they are under some, not extreme, calorie deficit. It is rare for children to be in negative nitrogen balance even when their daily consumption of protein is below 0.5 g per kg of body weight.
This suggests that, when children are in calorie deficit, they tend to hold on to protein stores (which are critical for growth), and shift their energy consumption to fat more easily than adults. The reason is that developmental growth powerfully stimulates protein synthesis. This leads to a hormonal mix that causes the body to be in anabolic state, even when other forces (e.g., calorie deficit, low protein intake) are pushing it into a catabolic state. In a sense, the tissues of children are always hungry for their building blocks, and they do not let go of them very easily.
The second reason is an interesting variation in the patterns of spontaneous hunger up-regulation in various athletes. The increase in hunger is generally lower for strength than endurance activities. The spontaneous increase for bodybuilders is among the lowest. Since being in a catabolic state tends to have a strong effect on hunger, increasing it significantly, these patterns suggest that strength exercise may actually contribute to placing one in an anabolic state. The duration of this effect is approximately 48 h. Some increase in hunger is expected, because of the increased calorie expenditure during and after strength exercise, but that is counterbalanced somewhat by the start of an anabolic state.
What is going on, and what does this mean for you?
One way to understand what is happening here is to think in terms of compensatory adaptation. Strength exercise, if done properly, tells the body that it needs more muscle protein. Calorie deficit, as long as it is short-term, tells the body that food supply is limited. The body’s short-term response is to keep muscle as much as possible, and use body fat to the largest extent possible to supply the body’s energy needs.
If the right stimuli are supplied in a cyclical manner, no long-term adaptations (e.g., lowered metabolism) will be “perceived” as necessary by the body. Let us consider a 2-day cycle where one does strength exercise on the first day, and rests on the second. A surplus of protein and calories on the first day would lead to both muscle and body fat gain. A deficit on the second day would lead to body fat loss, but not to muscle loss, as long as the deficit is not too extreme. Since only body fat is being lost, more is lost on the second day than on the first.
In this way, one can gain muscle and lose body fat at the same time, which is what seems to have happened with the participants of the Ballor et al. (1996) study. Or, one can keep muscle (not gaining any) and lose more body fat, with a slightly higher calorie deficit. If the calorie deficit is too high, one will enter negative nitrogen balance and lose both muscle and body fat, as often happens with natural bodybuilders in the pre-tournament “cutting” phase.
In a sense, the increase in protein synthesis stimulated by strength exercise is analogous to, although much less strong than, the increase in protein synthesis stimulated by the growth process in children.
References
Ballor, D.L., Harvey-Berino, J.R., Ades, P.A., Cryan, J., & Calles-Escandon, J. (1996). Contrasting effects of resistance and aerobic training on body composition and metabolism after diet-induced weight loss. Metabolism, 45(2), 179-183.
Brooks, G.A., Fahey, T.D., & Baldwin, K.M. (2005). Exercise physiology: Human bioenergetics and its applications. Boston, MA: McGraw-Hill.
What that post does not look into is whether strength exercise, performed at the anaerobic range, increases nitrogen balance. If it did, it may lead to a counterintuitive effect: strength exercise, when practiced at a certain level of intensity, might enable individuals in calorie deficit to retain their muscle, and lose primarily body fat. That is, strength exercise might push the body into burning more body fat and less muscle than it would normally do under calorie deficit conditions.
(Strength exercise combined with a small calorie deficit may be one of the best approaches for body fat loss in women. Photo source: complete-strength-training.com)
Under calorie deficit people normally lose both body fat and muscle to meet caloric needs. About 25 percent of lean body mass is lost in sedentary individuals, and 33 percent or more in individuals performing endurance exercise. I suspect that strength exercise has the potential to either bring this percentage down to zero, or to even lead to muscle gain if the calorie deficit is very small. One of the reasons is the data summarized on this post.
Two other reasons are related to what happens with children, and the variation in spontaneous hunger up-regulation in response to various types of exercise. The first reason can be summarized as this: it is very rare for children to be in negative nitrogen balance (Brooks et al., 2005); even when they are under some, not extreme, calorie deficit. It is rare for children to be in negative nitrogen balance even when their daily consumption of protein is below 0.5 g per kg of body weight.
This suggests that, when children are in calorie deficit, they tend to hold on to protein stores (which are critical for growth), and shift their energy consumption to fat more easily than adults. The reason is that developmental growth powerfully stimulates protein synthesis. This leads to a hormonal mix that causes the body to be in anabolic state, even when other forces (e.g., calorie deficit, low protein intake) are pushing it into a catabolic state. In a sense, the tissues of children are always hungry for their building blocks, and they do not let go of them very easily.
The second reason is an interesting variation in the patterns of spontaneous hunger up-regulation in various athletes. The increase in hunger is generally lower for strength than endurance activities. The spontaneous increase for bodybuilders is among the lowest. Since being in a catabolic state tends to have a strong effect on hunger, increasing it significantly, these patterns suggest that strength exercise may actually contribute to placing one in an anabolic state. The duration of this effect is approximately 48 h. Some increase in hunger is expected, because of the increased calorie expenditure during and after strength exercise, but that is counterbalanced somewhat by the start of an anabolic state.
What is going on, and what does this mean for you?
One way to understand what is happening here is to think in terms of compensatory adaptation. Strength exercise, if done properly, tells the body that it needs more muscle protein. Calorie deficit, as long as it is short-term, tells the body that food supply is limited. The body’s short-term response is to keep muscle as much as possible, and use body fat to the largest extent possible to supply the body’s energy needs.
If the right stimuli are supplied in a cyclical manner, no long-term adaptations (e.g., lowered metabolism) will be “perceived” as necessary by the body. Let us consider a 2-day cycle where one does strength exercise on the first day, and rests on the second. A surplus of protein and calories on the first day would lead to both muscle and body fat gain. A deficit on the second day would lead to body fat loss, but not to muscle loss, as long as the deficit is not too extreme. Since only body fat is being lost, more is lost on the second day than on the first.
In this way, one can gain muscle and lose body fat at the same time, which is what seems to have happened with the participants of the Ballor et al. (1996) study. Or, one can keep muscle (not gaining any) and lose more body fat, with a slightly higher calorie deficit. If the calorie deficit is too high, one will enter negative nitrogen balance and lose both muscle and body fat, as often happens with natural bodybuilders in the pre-tournament “cutting” phase.
In a sense, the increase in protein synthesis stimulated by strength exercise is analogous to, although much less strong than, the increase in protein synthesis stimulated by the growth process in children.
References
Ballor, D.L., Harvey-Berino, J.R., Ades, P.A., Cryan, J., & Calles-Escandon, J. (1996). Contrasting effects of resistance and aerobic training on body composition and metabolism after diet-induced weight loss. Metabolism, 45(2), 179-183.
Brooks, G.A., Fahey, T.D., & Baldwin, K.M. (2005). Exercise physiology: Human bioenergetics and its applications. Boston, MA: McGraw-Hill.
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